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1

Challenging the management of drug-resistant tuberculosis

Kim, Hannah Yejin, Heysell, Scott K, Mpagama, Stella, Marais, Ben J, Alffenaar, Jan-Willem

Journal:

Lancet (London, England)

Year:

2020

File:

PDF, 153 KB

2020

2

Should we worry for bedaquiline exposure in the treatment of MDR- and XDR-TB?

Alffenaar, Jan-Willem C., Akkerman, Onno W., Tiberi, Simon, Sotgiu, Giovanni, Migliori, Giovanni Battista

Journal:

European Respiratory Journal

Year:

2019

Language:

english

File:

PDF, 407 KB

english, 2019

3

Pharmacokinetic Drug Interactions of Antimicrobial Drugs: A Systematic Review on Oxazolidinones, Rifamycines, Macrolides, Fluoroquinolones, and Beta-Lactams

Bolhuis, Mathieu S., Panday, Prashant N., Pranger, Arianna D., Kosterink, Jos G. W., Alffenaar, Jan-Willem C.

Journal:

Year:

2011

Language:

english

File:

PDF, 531 KB

english, 2011

4

Antituberculosis Drug-induced Liver Injury in Children

Gafar, Fajri, Arifin, Helmi, Jurnalis, Yusri D., Yani, Finny F., Fitria, Najmiatul, Alffenaar, Jan-Willem C., Wilffert, Bob

Journal:

Pediatric Infectious Disease Journal

Year:

2019

Language:

english

File:

PDF, 120 KB

english, 2019

5

Population pharmacokinetics and limited sampling strategy for first-line tuberculosis drugs and moxifloxacin

Magis-Escurra, C., Later-Nijland, H.M.J., Alffenaar, J.W.C., Broeders, J., Burger, D.M., van Crevel, R., Boeree, M.J., Donders, A.R.T., van Altena, R., van der Werf, T.S., Aarnoutse, R.E.

Journal:

International Journal of Antimicrobial Agents

Year:

2014

Language:

english

File:

PDF, 205 KB

english, 2014

6

Quantification of amikacin and kanamycin in serum using a simple and validated LC–MS/MS method

Dijkstra, Jacob A, Sturkenboom, Marieke GG, Hateren, Kai van, Koster, Remco A, Greijdanus, Ben, Alffenaar, Jan-Willem C

Journal:

Year:

2014

Language:

english

File:

PDF, 935 KB

english, 2014

7

What is the right blood hematocrit preparation procedure for standards and quality control samples for dried blood spot analysis?

Koster, Remco A, Alffenaar, Jan-Willem C, Botma, Rixt, Greijdanus, Ben, Touw, Daan J, Uges, Donald RA, Kosterink, Jos GW

Journal:

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

8

Current status and opportunities for therapeutic drug monitoring in the treatment of tuberculosis

Zuur, Marlanka A., Bolhuis, Mathieu S., Anthony, Richard, den Hertog, Alice, van der Laan, Tridia, Wilffert, B., de Lange, Wiel, van Soolingen, Dick, Alffenaar, Jan-Willem C.

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2016

Language:

english

File:

PDF, 841 KB

english, 2016

9

Drug monitoring and individual dose optimization of antimicrobial drugs: oxazolidinones

Cattaneo, Dario, Alffenaar, Jan-Willem, Neely, Michael

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2016

Language:

english

File:

PDF, 757 KB

english, 2016

10

Therapeutic Drug Monitoring of Posaconazole: an Update

Dekkers, Bart G. J., Bakker, Martijn, van der Elst, Kim C. M., Sturkenboom, Marieke G. G., Veringa, Anette, Span, Lambert F. R., Alffenaar, Jan-Willem C.

Journal:

Current Fungal Infection Reports

Year:

2016

Language:

english

File:

PDF, 546 KB

english, 2016

11

Bioavailability of voriconazole in hospitalised patients

Veringa, Anette, Geling, Sanne, Span, Lambert F.R., Vermeulen, Karin M., Zijlstra, Jan G., van der Werf, Tjip S., Kosterink, Jos G.W., Alffenaar, Jan-Willem C.

Journal:

International Journal of Antimicrobial Agents

Year:

2016

Language:

english

File:

PDF, 220 KB

english, 2016

12

Dried blood spot validation of five immunosuppressants, without hematocrit correction, on two LC–MS/MS systems

Koster, Remco A, Veenhof, Herman, Botma, Rixt, Hoekstra, Alle Tjipke, Berger, Stefan P, Bakker, Stephan JL, Alffenaar, Jan-Willem C, Touw, Daan J

Journal:

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

13

Bedaquiline Resistance: Its Emergence, Mechanism, and Prevention

Nguyen, Thi Van Anh, Anthony, Richard M, Bañuls, Anne-Laure, Nguyen, Thi Van Anh, Vu, Dinh Hoa, Alffenaar, Jan-Willem C

Journal:

Clinical Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 179 KB

english, 2017

14

Lack of penetration of amikacin into saliva of tuberculosis patients

van den Elsen, Simone H.J., Akkerman, Onno W., Huisman, Justine R., Touw, Daan J., van der Werf, Tjip S., Bolhuis, Mathieu S., Alffenaar, Jan-Willem C.

Journal:

European Respiratory Journal

Year:

2018

Language:

english

File:

PDF, 305 KB

english, 2018

15

Pound foolish and penny wise—when will dosing of rifampicin be optimised?

Magis-Escurra, Cecile, Anthony, Richard M, van der Zanden, Adri G M, van Soolingen, Dick, Alffenaar, Jan-Willem C

Journal:

The Lancet Respiratory Medicine

Year:

2018

Language:

english

File:

PDF, 214 KB

english, 2018

16

The role of therapeutic drug monitoring in treatment optimization in tuberculosis and diabetes mellitus co-morbidity

Dekkers, B. G. J., Akkerman, O. W., Alffenaar, J. W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 832 KB

english, 2018

17

Predictors for treatment outcomes among patients with drug-susceptible tuberculosis in the Netherlands: a retrospective cohort study

Pradipta, I.S., van't Boveneind-Vrubleuskaya, N., Akkerman, O.W., Alffenaar, J.W.C., Hak, E.

Journal:

Clinical Microbiology and Infection

Year:

2018

Language:

english

File:

PDF, 662 KB

english, 2018

18

Linezolid-based Regimens for Multidrug-resistant Tuberculosis (TB): A Systematic Review to Establish or Revise the Current Recommended Dose for TB Treatment

Bolhuis, Mathieu S, Akkerman, Onno W, Sturkenboom, Marieke G G, Ghimire, Samiksha, Srivastava, Shashikant, Gumbo, Tawanda, Alffenaar, Jan-Willem C

Journal:

Clinical Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 4.28 MB

english, 2018

19

Therapeutic Drug Monitoring Can Improve Linezolid Dosing Regimens in Current Clinical Practice

Rao, Gauri G, Konicki, Robyn, Cattaneo, Dario, Alffenaar, Jan-Willem, Marriott, Deborah JE, Neely, Michael

Journal:

Therapeutic Drug Monitoring

Year:

2019

File:

PDF, 1.11 MB

2019

20

Pharmacokinetic Modeling, Simulation, and Development of a Limited Sampling Strategy of Cycloserine in Patients with Multidrug-/Extensively Drug-Resistant Tuberculosis

van der Galiën, Ruben, Boveneind-Vrubleuskaya, Natasha van’t, Peloquin, Charles, Skrahina, Alena, Touw, Daan J., Alffenaar, Jan-Willem C.

Journal:

Clinical Pharmacokinetics

Year:

2020

Language:

english

File:

PDF, 995 KB

english, 2020

21

Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases

Tadolini, Marina, Codecasa, Luigi Ruffo, GarcÃa-GarcÃa, JosÃ©-MarÃa, Blanc, FranÃ§ois-Xavier, Borisov, Sergey, Alffenaar, Jan-Willem, AndrÃ©jak, Claire, Bachez, Pierre, Bart, Pierre-Alexandre, Beli

Journal:

European Respiratory Journal

Year:

2020

File:

PDF, 312 KB

2020

22

Simultaneous determination of clarithromycin, rifampicin and their main metabolites in human plasma by liquid chromatography–tandem mass spectrometry

Femke de Velde, Jan-Willem C. Alffenaar, A. Mireille A. Wessels, Ben Greijdanus, Donald R.A. Uges

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 168 KB

english, 2009

23

Method for therapeutic drug monitoring of azole antifungal drugs in human serum using LC/MS/MS

J.W.C. Alffenaar, A.M.A. Wessels, K. van Hateren, B. Greijdanus, J.G.W. Kosterink, D.R.A. Uges

Journal:

Journal of Chromatography B

Year:

2010

Language:

english

File:

PDF, 317 KB

english, 2010

24

Determination of moxifloxacin in dried blood spots using LC–MS/MS and the impact of the hematocrit and blood volume

D.H. Vu, R.A. Koster, J.W.C. Alffenaar, J.R.B.J. Brouwers, D.R.A. Uges

Journal:

Journal of Chromatography B

Year:

2011

Language:

english

File:

PDF, 506 KB

english, 2011

25

Validation parameters cannot be obtained without using pure substance

Kim C.M. van der Elst, Donald R.A. Uges, Jan-Willem C. Alffenaar

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2011

Language:

english

File:

PDF, 110 KB

english, 2011

26

Pharmacokinetic drug interactions of azoles

Roger J. M. Brüggemann, Jan-Willem C. Alffenaar, Nicole M. A. Blijlevens, Eliane M. Billaud, Jos G. W. Kosterink, Paul E. Verweij, David M. Burger

Journal:

Current Fungal Infection Reports

Year:

2008

Language:

english

File:

PDF, 405 KB

english, 2008

27

Linezolid is not suitable as internal standard

J.W.C. Alffenaar, B. Greijdanus

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2010

Language:

english

File:

PDF, 78 KB

english, 2010

28

High voriconazole trough levels in relation to hepatic function: how to adjust the dosage?

Jan-Willem C. Alffenaar, Tessa De Vos, Donald R. A. Uges, Simon M. G. J. Daenen

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

29

Phenytoin-induced reduction of voriconazole serum concentration is not compensated by doubling the dosage

Jan-Willem C. Alffenaar, Kim C. M. Van Der Elst, Donald R. A. Uges, Jos G. W. Kosterink, Simon M. G. J. Daenen

Journal:

British Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 238 KB

english, 2009

30

Plasma concentrations of caspofungin at two different dosage regimens in a patient with hepatic dysfunction

K.C.M. van der Elst, R.J.M. Brüggemann, M.G.G. Rodgers, J.W.C. Alffenaar

Journal:

Transplant Infectious Disease

Year:

2012

Language:

english

File:

PDF, 77 KB

english, 2012

31

Pyridoxine induces non-specific EEG alterations in infants with therapy resistant seizures

L.K. Teune, J.H. vd Hoeven, N.M. Maurits, A.F. Bos, J.W.C. Alffenaar, D.J. Reijngoud, O.F. Brouwer, D.A. Sival

Journal:

Year:

2007

Language:

english

File:

PDF, 273 KB

english, 2007

32

Determination of ribavirin in human serum using liquid chromatography tandem mass spectrometry

Henk van der Lijke, Jan-Willem C. Alffenaar, Wim Th. Kok, Ben Greijdanus, Donald R.A. Uges

Journal:

Year:

2012

Language:

english

File:

PDF, 324 KB

english, 2012

33

Antimicrobial drugs for Buruli ulcer – Authors' reply

Tjip van der Werf, Willemien Nienhuis, Jan Willem Alffenaar, Deepak Almeida, Ymkje Stienstra

Journal:

Year:

2010

Language:

english

File:

PDF, 117 KB

english, 2010

34

106 Pharmacokinetic variability of clarithromycin is due to differences in CYP3A4 activity in patients with cystic fibrosis (CF) – a reason for treatment failure?

C.S. Dalbøge, X.C. Nielsen, K. Dalhoff, M. Dunø, A. Buchara, J.-W.C. Alffenaar, T. Pressler, N. Høiby, H.K. Johansen

Journal:

Journal of Cystic Fibrosis

Year:

2011

Language:

english

File:

PDF, 48 KB

english, 2011

35

Comparison of the Pharmacokinetics of Two Dosage Regimens of Linezolid in Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis Patients

Jan-Willem C. Alffenaar, Richard van Altena, Ilse M. Harmelink, Patricia Filguera, Esther Molenaar, A. Mireille A. Wessels, Dick van Soolingen, Jos G. W. Kosterink, Donald R. A. Uges, Tjip S. van der

Journal:

Clinical Pharmacokinetics

Year:

2010

Language:

english

File:

PDF, 165 KB

english, 2010

36

Fast LC-MS/MS analysis of tacrolimus, sirolimus, everolimus and cyclosporin A in dried blood spots and the influence of the hematocrit and immunosuppressant concentration on recovery

Koster, Remco A., Alffenaar, Jan-Willem C., Greijdanus, Ben, Uges, Donald R.A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.50 MB

english, 2013

37

Troubleshooting carry-over of LC–MS/MS method for rifampicin, clarithromycin and metabolites in human plasma

Vu, D.H., Koster, R.A., Wessels, A.M.A., Greijdanus, B., Alffenaar, J.W.C., Uges, D.R.A.

Journal:

Journal of Chromatography B

Year:

2013

Language:

english

File:

PDF, 264 KB

english, 2013

38

Efficacy, safety and tolerability of linezolid containing regimens in treating MDR-TB and XDR-TB: systematic review and meta-analysis

Sotgiu, G., Centis, R., D'Ambrosio, L., Alffenaar, J.-W. C., Anger, H. A., Caminero, J. A., Castiglia, P., De Lorenzo, S., Ferrara, G., Koh, W.-J., Schecter, G. F., Shim, T. S., Singla, R., Skrahina,

Journal:

European Respiratory Journal

Year:

2012

Language:

english

File:

PDF, 166 KB

english, 2012

39

Simultaneous determination of rifampicin, clarithromycin and their metabolites in dried blood spots using LC–MS/MS

Vu, D.H., Koster, R.A., Bolhuis, M.S., Greijdanus, B., Altena, R.V., Nguyen, D.H., Brouwers, J.R.B.J., Uges, D.R.A., Alffenaar, J.W.C

Journal:

Year:

2014

Language:

english

File:

PDF, 906 KB

english, 2014

40

Pharmacokinetic studies in patients with nontuberculous mycobacterial lung infections

Magis-Escurra, C., Alffenaar, J.W., Hoefnagels, I., Dekhuijzen, P.N.R., Boeree, M.J., van Ingen, J., Aarnoutse, R.E.

Journal:

International Journal of Antimicrobial Agents

Year:

2013

Language:

english

File:

PDF, 509 KB

english, 2013

41

Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents

Brüggemann, Roger J. M., Alffenaar, Jan‐Willem C., Blijlevens, Nicole M. A., Billaud, Eliane M., Kosterink, Jos G. W., Verweij, Paul E., Burger, David M.

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

42

Rifampicin and moxifloxacin for tuberculous meningitis

Akkerman, Onno, Pranger, Arianna, van Altena, Richard, van der Werf, Tjip, Alffenaar, Jan-Willem

Journal:

The Lancet Infectious Diseases

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

43

Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis

Dalbøge, C.S., Nielsen, X.C., Dalhoff, K., Alffenaar, J.W., Duno, M., Buchard, A., Uges, D.R.A., Jensen, A.G., Jürgens, G., Pressler, T., Johansen, H.K., Høiby, N.

Journal:

Journal of Cystic Fibrosis

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

44

78 Pharmacokinetic variability of clarithromycin and ciprofloxacin in patients with cystic fibrosis (CF)

Dalbøge, C.S., Nielsen, X.C., Dalhoff, K., Alffenaar, J.-W., Duno, M., Buchard, A., Uges, D.R.A., Jensen, A.G., Jürgens, G., Pressler, T., Høiby, N., Johansen, H.K.

Journal:

Journal of Cystic Fibrosis

Year:

2013

Language:

english

File:

PDF, 69 KB

english, 2013

45

THE BATTLE OF THE CLUBS.

Dalbøge, C.S., Nielsen, X.C., Dalhoff, K., Alffenaar, J.-W., Duno, M., Buchard, A., Uges, D.R.A., Jensen, A.G., Jürgens, G., Pressler, T., Høiby, N., Johansen, H.K.

Journal:

Year:

1897

Language:

english

File:

PDF, 424 KB

english, 1897

46

Trimethoprim/sulfamethoxazole susceptibility of Mycobacterium tuberculosis

Alsaad, N., van der Laan, T., van Altena, R., Wilting, K.R., van der Werf, T.S., Stienstra, Y., van Soolingen, D., Alffenaar, J.W.C.

Journal:

International Journal of Antimicrobial Agents

Year:

2013

Language:

english

File:

PDF, 89 KB

english, 2013

47

Efficacy and safety of meropenem-clavulanate added to linezolid-containing regimens in the treatment of MDR-/XDR-TB

De Lorenzo, S., Alffenaar, J. W., Sotgiu, G., Centis, R., D'Ambrosio, L., Tiberi, S., Bolhuis, M. S., van Altena, R., Viggiani, P., Piana, A., Spanevello, A., Migliori, G. B.

Journal:

European Respiratory Journal

Year:

2013

Language:

english

File:

PDF, 254 KB

english, 2013

48

In vitro synergy between linezolid and clarithromycin against Mycobacterium tuberculosis

Bolhuis, M. S., van der Laan, T., Kosterink, J. G. W., van der Werf, T. S., van Soolingen, D., Alffenaar, J.-W. C.

Journal:

European Respiratory Journal

Year:

2014

Language:

english

File:

PDF, 193 KB

english, 2014

49

Five year results of an international proficiency testing programme for measurement of antifungal drug concentrations

Lempers, V. J. C., Alffenaar, J. W. C., Touw, D. J., Burger, D. M., Uges, D. R. A., Aarnoutse, R. E., Bruggemann, R. J. M.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2014

Language:

english

File:

PDF, 247 KB

english, 2014

50

Quantification and Validation of Ertapenem Using a Liquid Chromatography-Tandem Mass Spectrometry Method

van Rijn, S. P., Wessels, A. M. A., Greijdanus, B., Touw, D. J., Alffenaar, J. W. C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2014

Language:

english

File:

PDF, 306 KB

english, 2014

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